Acrylic acids and derivatives
Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | MFCD09833218 | >99.91% | 649.70 | 50 MG
Vicriviroc maleate is a potent, selective, oral bioavailable, and central nervous system (CNS) penetrated antagonist of CCR5, with a Ki of 2.5 nM. It also inhibits HIV-1 in peripheral blood mononuclear cells (PBMC).
- Potent and selective CCR5 antagonist.
- Oral bioavailable and CNS penetrated.
- Inhibits HIV-1 in PBMC cells.
- Shows mean IC50 of 0.45 nM and IC90 of 4 nM for a panel of HIV isolates.
- Exhibits weak activity against hERG (IC50, 5.8 μM).
- Inhibits chemotactic response to MIP-1α with IC50 values below 1 nM.
- Suppresses RANTES-induced signaling with a mean IC50 of 4.2 ± 1.3 nM.
- Potently suppresses tested viral isolates with geometric mean EC50s of 0.04-2.3 nM and IC90s of 0.45-18 nM.
- Demonstrates good oral availability in rats and monkeys, with no acute CNS or GI effects at 10 mg/kg dose.
Medchemexpress LLC 7-O-Ethylmorroniside | 945721-10-8 | 5 MG
7-O-Ethylmorroniside is an iridoid glucoside isolated from the fruit of *Cornus officinalis*, which is traditionally used in Chinese medicine. This compound is primarily researched for its potential in treating kidney diseases, including diabetic nephropathy.
- Iridoid glucoside
- Isolated from the fruit of *Cornus officinalis*
- High purity of 99.91% (HPLC)
- Researched for kidney diseases, including diabetic nephropathy
eMolecules 77313-10-1 | Ambeed | Dimethyl 3-aminopentanedioate hydrochloride | 1g | 491615496 | A127385 | MFCD14705045 | 211.64 | C7H14ClNO4
Ambeed | Dimethyl 3-aminopentanedioate hydrochloride | 1g | 491615496 | A127385 | 77313-10-1 | MFCD14705045 | 211.640 | C7H14ClNO4
Cayman Chemical trns-Indole-3-acrylIc AcId 10g
A metabolite of L-tryptophan; increases the levels of mRNA encoding mucin 2 and Il-10, as well as decreases mRNA encoding Tnf-α, in primary mouse large intestinal spheroids co-cultured with LPS-stimulated primary mouse BMDMs; has been used as a precursor in the synthesis of anticancer agents and tubulin polymerization inhibitors, as well as used as a reactive chromophore probe to assess the α and β subunit conformational changes of S. typhimurium tryptophan synthase in tryptophan biosynthesis
Medchemexpress LLC HY-101858 5mg Medchemexpress, BQCA CAS:338747-41-4 Purity:>98%
Medchemexpress, HY-101858 5mg BQCA CAS:338747-41-4 BQCA a highly selective allosteric modulator of the M1 mAChR. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 3-Bromopyridin-2-ol | 13466-43-8 | 174.00 | 5 G
3-Bromopyridin-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- For research use only
- Can be used as a biological material or organic compound for life science related research
- Listed under biochemical assay reagents
Medchemexpress LLC 3-amino-6-bromopyridine | 13534-97-9 | MFCD01646116 | 99.1% | 173.01 g/mol | C5H5BrN2 | 25 G
6-Bromopyridin-3-amine is an organic building block and research reagent used in medicinal chemistry and synthetic organic chemistry. Supplied as a high-purity solid, it serves as an intermediate for the preparation of brominated heterocycles and related derivatives, with documentation available for batch quality and safety.
- High reported purity (~99.1%).
- Molecular weight 173.01 g/mol.
- Chemical formula C5H5BrN2.
- Available in multiple lab-scale pack sizes for flexibility.
- Certificate of analysis and safety data sheet available.
Medchemexpress LLC HY-B0298A 100mg Medchemexpress, Clemastine (fumarate) Meclastine fumarate CAS:14976-57-9 Purity:98%
Medchemexpress,HY-B0298A 100mg Clemastine (fumarate) Meclastine fumarate CAS:14976-57-9 Formula:C25H30ClNO5 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15232B 100mg Medchemexpress, GS-7340 (hemifumarate) Tenofovir alafenamide hemifumarate CAS:1392275-56-7 Purity:98%
Medchemexpress,HY-15232B 100mg GS-7340 (hemifumarate) Tenofovir alafenamide hemifumarate CAS:1392275-56-7 Formula:C21H29N6O5P.1/2 C4H4O4 GS-7340 (Tenofovir alafenamide) hemifumarate is an investigational oral prodrug of the HIV-1 nucleotide reverse transcriptase inhibitor Tenofovir (TFV). Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 682741-29-3 | Medchem Express | HTS01037 | 5mg | 446256952 | HY-101503 | MFCD02681826 | 337.36 | C14H11NO5S2
Medchem Express | HTS01037 | 5mg | 446256952 | HY-101503 | 682741-29-3 | MFCD02681826 | 337.360 | C14H11NO5S2
Medchemexpress LLC HY-N1363 25mg Medchemexpress, Royal Jelly acid CAS:14113-05-4 Purity:>98%
Medchemexpress, HY-N1363 25mg Royal Jelly acid CAS:14113-05-4 Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 3-Amino-2-chloropyridine | 6298-19-7 | MFCD00006238 | 100.0% | 128.56 g/mol | C5H5ClN2 | 250g
2-Chloropyridin-3-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Eplivanserin hemifumarate | 130580-02-8 | 98.1% | 386.43 g·mol⁻1 | C19H21FN2O2·1/2C4H4O4 | 5 MG
Eplivanserin hemifumarate is a research-grade small molecule described as a potent, selective, orally active 5-HT2A receptor antagonist. Supplied as the hemifumarate salt in solid form, it is intended for preclinical and in vitro pharmacology studies and comes with an accompanying purity specification and solubility information for assay preparation.
- Potent, selective 5-HT2A receptor antagonist suitable for receptor pharmacology studies.
- Supplied as hemifumarate salt in solid form for handling and storage.
- High purity (~98.1%) appropriate for research applications.
- Soluble in DMSO at 25 mg/mL; sonication and gentle heating aid dissolution.
- Available in small pack sizes tailored for preclinical and in vitro work.
eMolecules 241127-79-7 | Medchem Express | NSC689857 | 5mg | 778475729 | HY-123578 | 407.51 | C25H29NO4
Medchem Express | Physostigmine (salicylate) | 5mg | 586608775 | HY-B1266 | 57-64-7 | MFCD00135659 | 413.474 | C22H27N3O5
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eMolecules 221297-82-1 | 3-Bromo-4-chloropyridin-2-amine | Ambeed | MFCD15143381 | 207.460 | C5H4BrClN2 | 98.000 | Nc1nccc(Cl)c1Br | 250mg | 552600702
3-Bromo-4-chloropyridin-2-amine | Ambeed | 221297-82-1 | MFCD15143381 | 207.460 | C5H4BrClN2 | 98.000 | Nc1nccc(Cl)c1Br | 250mg | 552600702